Antibody Humanizer
v0.1.0Humanize murine antibody sequences using CDR grafting and framework optimization to reduce immunogenicity while preserving antigen binding. Predicts optimal...
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byAIpoch@aipoch-ai
MIT-0
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LicenseMIT-0 · Free to use, modify, and redistribute. No attribution required.
Security Scan
OpenClaw
Benign
medium confidencePurpose & Capability
The name/description (humanize murine antibodies via CDR grafting and framework optimization) matches the included instructions and the Python implementation: sequence validation, CDR extraction, framework matching, scoring, and back-mutation prediction. No surprising binaries or unrelated capabilities are requested.
Instruction Scope
SKILL.md instructs local analysis of sequences and example API usage consistent with the stated purpose. The instructions do not direct the agent to read system credentials, configuration files, or exfiltrate data to external endpoints. The allowed-tools list includes Read/Write/Bash/Edit (expected for a local processing skill) but the runtime instructions themselves stay within the domain of sequence processing.
Install Mechanism
No install spec is provided (instruction-only + included script), so nothing is automatically downloaded or executed during install. A single Python script is included; it uses only standard libraries and local data structures. This is low-install risk. Note: requirements.txt lists dataclasses and enum which are part of modern Python stdlib and not evidence of third-party download.
Credentials
The skill declares no required environment variables, credentials, or config paths. The code does not import networking libraries or attempt to read environment variables—requested privileges are minimal and proportionate to processing sequences locally.
Persistence & Privilege
Skill is not marked always:true and does not request persistent system presence or modify other skill/config files. Autonomous invocation is allowed (platform default) but not combined with other elevated privileges.
Assessment
This skill appears internally consistent and runs local sequence-processing logic only, but take these precautions before installing or using it: 1) Review the full scripts/main.py yourself (or have a trusted developer do so) before running, especially if you will provide confidential sequences. 2) Run the tool in an isolated environment (container/VM) if you are unsure about provenance—the registry metadata shows no homepage and the source is 'unknown'. 3) Do not treat outputs as experimentally validated: humanization recommendations require laboratory confirmation and regulatory review before therapeutic use. 4) Ensure using the tool complies with your institutional/ethical guidelines for handling potentially sensitive biological sequence data. 5) Note the requirements.txt entries (dataclasses, enum) are standard library modules for Python 3.7+—no external packages appear required.Like a lobster shell, security has layers — review code before you run it.
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License
MIT-0
Free to use, modify, and redistribute. No attribution required.