{"skill":{"slug":"crispr-screen-analyzer","displayName":"Crispr Screen Analyzer","summary":"Process CRISPR screening data to identify essential genes and hit candidates. Performs quality control, statistical analysis (RRA), and hit calling for poole...","tags":{"latest":"0.1.0"},"stats":{"comments":0,"downloads":177,"installsAllTime":0,"installsCurrent":0,"stars":0,"versions":1},"createdAt":1773806081218,"updatedAt":1773807406708},"latestVersion":{"version":"0.1.0","createdAt":1773806081218,"changelog":"crispr-screen-analyzer 0.1.0 – Initial release\n\n- Analyze pooled CRISPR screening data for essential gene and hit candidate identification.\n- Provides quality control metrics (Gini index, read depth, dropout rates).\n- Supports Robust Rank Aggregation (RRA) for statistical analysis of sgRNA enrichment/depletion.\n- Calculates log2 fold changes and applies FDR/fold-change thresholds for hit calling.\n- Compatible with multiple treatment/control groups and replicates.","license":"MIT-0"},"metadata":null,"owner":{"handle":"aipoch-ai","userId":"s17fjw78yq6wtd4ep6zsaxwrn983hznr","displayName":"AIpoch","image":"https://avatars.githubusercontent.com/u/258999481?v=4"},"moderation":null}