{"skill":{"slug":"antibody-engineering","displayName":"Antibody Engineering","summary":"Antibody engineering workflow combining ANARCI, BioPhi, IgFold, FoldX, and Rosetta tools through SciMiner.","tags":{"latest":"1.0.1"},"stats":{"comments":0,"downloads":94,"installsAllTime":0,"installsCurrent":0,"stars":3,"versions":2},"createdAt":1776962386557,"updatedAt":1777080106533},"latestVersion":{"version":"1.0.1","createdAt":1777079545585,"changelog":"**Expanded with Rosetta-guided design and developability profiling for antibody engineering.**\n\n- Added Rosetta FastRelax, SAP Score, FastDesign, and InterfaceAnalyzer tools for advanced structure relaxation, aggregation risk assessment, precision redesign, and interface analysis.\n- Updated workflow to include structure relaxation after modeling, SAP hydrophobicity screening, and Rosetta-based precision design phases.\n- Clarified boundaries and integration between ANARCI/BioPhi (sequence), IgFold/FoldX (structure/energy), and Rosetta (refinement/scoring).\n- Emphasized multi-objective prioritization balancing affinity, stability, immunogenicity, and aggregation risk.\n- Updated tool descriptions and recommended workflow for new and expanded Rosetta integrations.","license":"MIT-0"},"metadata":{"os":null,"systems":null},"owner":{"handle":"sciminer","userId":"s170qp1q4twz35wa85ppa8894h83w461","displayName":"SciMiner","image":null},"moderation":null}